Treatment of early childhood medulloblastoma by postoperative chemotherapy and deferred radiotherapy
نویسندگان
چکیده
منابع مشابه
Treatment of Early Childhood Medulloblastoma by Postoperative Chemotherapy Alone—A Critical Review
Despite comprehensive treatment with surgery, radiation, and chemotherapy, medulloblastoma remains the most common malignant brain tumor in children with a fi ve-year disease free survival rate of only 40% in those less than 10 years of age. Although adjuvant regimens are an integral component in patient management, radiotherapy in very young children is limited by the susceptibility of the imm...
متن کاملPostoperative radiotherapy for paediatric medulloblastoma.
www.thelancet.com/oncology Published online August 11, 2016 http://dx.doi.org/10.1016/S1470-2045(16)30390-4 1 The proportion of children with medulloblastoma receiving deferred postoperative radiotherapy more than tripled in the USA from 2004 to 2012, according to new research. Benjamin Kann (Yale University School of Medicine, New Haven, CT, USA) and colleagues examined the records of 816 pati...
متن کاملChemotherapy for Childhood Medulloblastoma and Primitive Neuroectodermal Tumors.
Medulloblastoma is the most common form of childhood brain tumor, and management has evolved over the past two decades. Chemotherapy is now an integral part of the treatment of the majority, if not all, patients with this disease. Medulloblastoma is a chemosensitive tumor, and recurrent disease will often respond to a variety of different chemotherapeutic agents. The use of higher-dose chemothe...
متن کاملChemotherapy dose-intensity and survival for childhood medulloblastoma.
AIM To determine the relationship between prescribed dose-intensity of chemotherapy and survival in childhood medulloblastoma. MATERIALS AND METHODS A total of 55 trials from 1970-2009 were identified, 30 were eligible for analysis, with individual treatment regimes with 5-year (or more) outcome figures. Relationships of outcome to dose-intensity were analysed using weighted regression. RES...
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ژورنال
عنوان ژورنال: Neuro-Oncology
سال: 2009
ISSN: 1523-5866,1522-8517
DOI: 10.1215/15228517-2008-084